S-2-[[[(1,1-diMethylethyl)diMethylsilyl]oxy]diphenylMethyl]-Pyrrolidine
Pyrrolidine, 2-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]diphenylmethyl]-,(2S)-
CAS: 864466-71-7
Molecular Formula: C23H33NOSi
S-2-[[[(1,1-diMethylethyl)diMethylsilyl]oxy]diphenylMethyl]-Pyrrolidine - Names and Identifiers
S-2-[[[(1,1-diMethylethyl)diMethylsilyl]oxy]diphenylMethyl]-Pyrrolidine - Physico-chemical Properties
| Molecular Formula | C23H33NOSi |
| Molar Mass | 367.6 |
| Density | 0.998±0.06 g/cm3(Predicted) |
| Melting Point | 71-73°C |
| Boling Point | 445.2±35.0 °C(Predicted) |
| Flash Point | >110°C (>230°F) |
| BRN | 10368174 |
| pKa | 10.12±0.10(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Sensitive | 7: reacts slowly with moisture/water |
S-2-[[[(1,1-diMethylethyl)diMethylsilyl]oxy]diphenylMethyl]-Pyrrolidine - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
S-2-[[[(1,1-diMethylethyl)diMethylsilyl]oxy]diphenylMethyl]-Pyrrolidine - Introduction
Pyrrolidine, 2-[[[(1,1-dimenthylethyl) dimethylsilyl]oxy]diphenylmethyl]-,(2S)-, often abbreviated as S-Binol-pyrrolidine, is an organic compound. Its chemical formula is C27H35NOSi.
Nature:
S-Binol-pyrrolidine is a white solid, odorless. It is soluble in most organic solvents such as ethanol, chloroform and dichloromethane. It has a high melting and boiling point.
Use:
S-Binol-pyrrolidine are mainly used in asymmetric catalytic reactions in organic synthesis. It can be used as a ligand for metal-catalyzed reactions, such as asymmetric vinylation, oxamide reaction and asymmetric cation insertion reaction. In addition, it can also be used to study chiral recognition and enantiomeric separation.
Preparation Method:
The preparation of S-Binol-pyrrolidine is usually accomplished by a two-step reaction. First, diphenyl methyl ketone is reacted with tert-butyldimethylaminosilane to produce diphenyl (tert-butyldimethylaminosiloxy) methyl ketone. This intermediate is then reacted with pyrrolidine to give the final product S-Binol-pyrrolidine.
Safety Information:
S-Binol-pyrrolidine there are no clear toxicity data. However, as an organic compound, it is still necessary to pay attention to safety measures, such as wearing appropriate protective gloves and glasses, and avoiding direct contact with skin and eyes. At the same time, it should be operated in a well-ventilated place, away from fire and high temperature environment. For accidental contact or ingestion, seek medical attention promptly.
Nature:
S-Binol-pyrrolidine is a white solid, odorless. It is soluble in most organic solvents such as ethanol, chloroform and dichloromethane. It has a high melting and boiling point.
Use:
S-Binol-pyrrolidine are mainly used in asymmetric catalytic reactions in organic synthesis. It can be used as a ligand for metal-catalyzed reactions, such as asymmetric vinylation, oxamide reaction and asymmetric cation insertion reaction. In addition, it can also be used to study chiral recognition and enantiomeric separation.
Preparation Method:
The preparation of S-Binol-pyrrolidine is usually accomplished by a two-step reaction. First, diphenyl methyl ketone is reacted with tert-butyldimethylaminosilane to produce diphenyl (tert-butyldimethylaminosiloxy) methyl ketone. This intermediate is then reacted with pyrrolidine to give the final product S-Binol-pyrrolidine.
Safety Information:
S-Binol-pyrrolidine there are no clear toxicity data. However, as an organic compound, it is still necessary to pay attention to safety measures, such as wearing appropriate protective gloves and glasses, and avoiding direct contact with skin and eyes. At the same time, it should be operated in a well-ventilated place, away from fire and high temperature environment. For accidental contact or ingestion, seek medical attention promptly.
Last Update：2024-04-10 22:29:15
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Product Name: (S)-2-[[[(1,1-Dimethylethyl)dimethylsilyl]oxy]diphenylmethyl]pyrrolidine Request for quotationCAS: 864466-71-7
Tel: 15001012717
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